Lung diseases

Idiopathic Pulmonary Fibrosis is a chronic degenerative diseases of unknown etiology (Raghu, et al. 2011) , derived from lung parenchyma changes caused by epithelial activation of fibroblast migration, proliferation and differentiation into active myofibroblasts that secrete large amount of extracellular matrix components (Martinez, Fernando J., et al. 2017).
Here, you can see some genes that have been reported in the literature to be relevant for IPF. We used the following datasets: GSE32537 GSE21369 GSE24206 GSE94060 GSE72073 GSE35145 GSE31934.

Figure reported in X.

Chronic Obstructive Pulmonary Diseases is a progressive, irreversible and debilitating disease with a heterogeneous phenotype and multi factorial causes in which tabacco smoke is consider the main one. COPD patients have respiratory insufficiency and identification of chronic bronchitis and emphysema (Rennard, Stephen I., et al. 2015).